Our lab uses a variety of approaches to develop drugs from natural products. We collaborate with biologists and microbiologists to discover and develop potential drugs for treatment of cancer, malaria, leishmaniasis, and human African trypanosomiasis (sleeping sickness), and we also work to develop improved methods of drug delivery. These approaches are illustrated by the projects below.
Exploring the Merck library of natural product extracts to find and study potential new antimalarial agents
Using novel bioassay to discover inhibitors of the proteasome
A proposed new International Cooperative Biodiversity Group to discover antileishmanial and antitrypanosomal natural products from the marine and microbial biodiversity of South Africa.
Using gold nanoparticles to deliver anticancer drugs directly to the tumor site
The mission of the Virginia Tech Center for Drug Discovery (VTCDD) is: